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This section provides an overview for chromatographic gas as well as their applications and principles. Also, please take a look at the list of 12 chromatographic gas manufacturers and their company rankings. Here are the top-ranked chromatographic gas companies as of June, 2025: 1.PAC L.P., 2.Drawell Instrument Co., Ltd, 3.ELGA LabWater..
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Okayama University Graduate School, Ph.D. (Agriculture). After working as a specially appointed Assistant Professor at Tokyo Medical and Dental University, a fluid researcher at the Okayama Prefectural Institute of Biological Sciences, and a special researcher (JSPS PD) at the Japan Society for the Promotion of Japan Science, he became independent as a freelancer.
Specializes in natural product chemistry, protein engineering, fermentation engineering, and instrumental analysis of chemicals (especially mass spectrometry chemistry).
Thesis: https://pubmed.ncbi.nlm.nih.gov/?term=HIROKAZU+USUKI
linkedin: https://www.linkedin.com/in/%E5%8D%9A%E4%B8%80-%E8%87%BC%E6%9C%A8-b83827228/
A gas chromatograph is an instrument used for qualitative and quantitative analysis of easily vaporizable compounds. It is commonly abbreviated as gas chromatography and is sometimes written as GC, from the English abbreviation Gas Chromatograph. Along with high-performance liquid chromatography, it is a very well-known analytical technique.
Its principle is to vaporize a sample and then separate each component to determine the type and content of compounds. The greatest advantage of this method is that it can analyze volatile components even at very low concentrations. Currently, gas chromatographs are used in a wide range of fields, including pharmaceutical, food, and chemical industries, contributing to the foundation and development of science and technology.
Gas chromatography and gas chromatography are similar terms, and the two are often confused, but the former (gas chromatograph) refers to "experimental equipment" and the latter (gas chromatography) refers to "separation operations using gas chromatography".
Gas chromatographs are used for the separation and analysis of compounds in the fields of medicine, food, and chemistry. For example, it can be used to measure the concentration of hazardous substances and to analyze the components of gases generated in equipment. Note, however, that not all compounds can be analyzed. Due to its principle, gas chromatography generally cannot analyze non-volatile compounds with a boiling point of 400°C or higher, or unstable compounds that decompose at high temperatures. Inorganic metals, ions, and highly adsorbable compounds are also difficult to analyze for the same reason and must be confirmed before analysis.
The principle of gas chromatography is very simple and consists of the following three steps:
First, the liquid sample is thermally vaporized. The vaporized components are transported to the column by a carrier gas. The vaporized components are adsorbed and distributed to the stationary phase (liquid phase) in the column, separated by component, and passed through the column. Since the speed at which compounds move through the column differs depending on the compound, the components with the fastest movement speed are first separated from the column. Since each separated component is recorded as a peak by the detector, the type and concentration of the sample can be determined by comparing the retention time and peak area with those of the standard.
The main feature of this analytical method is that it can analyze volatile components that cannot be separated, identified, or quantitated by high-performance liquid chromatography.
The selection of the stationary phase to be used in the column of gas chromatography is very important. If a column with an appropriate stationary phase is not used according to the characteristics of the components, separation and analysis will be difficult.
Columns are broadly classified into two types based on the polarity of the stationary phase: nonpolar columns and highly polar columns.
A non-polar column is a column in which a compound with low polarity is used as the stationary phase. In such columns, low-polarity compounds are strongly retained in the low-polarity liquid phase as the stationary phase, resulting in slower migration rates and, thus, higher separation performance. Therefore, non-polar columns are suitable for the analysis of nonpolar compounds. In addition, nonpolar columns are more heat resistant than highly polar columns and can generally be used up to 350°C.
A highly polar column is a column in which a highly polar compound is used as the stationary phase. In such columns, highly polar compounds are strongly retained, which slows down their migration rate and results in high separation performance. As a result, these columns are suitable for the analysis of highly polar compounds. Also note that high polarity columns have low heat resistance, generally with an upper limit of around 250°C.
Due to their low volatility, highly polar organic low-molecular-weight compounds are generally difficult to separate and analyze using gas chromatography. However, depending on the structure of the target compound, it may be possible to derivatize it into a volatile compound using chemical methods, in which case separation using gas chromatography becomes possible. Therefore, such derivatization techniques are widely used for separating and analyzing compounds that are difficult to separate by high-performance liquid chromatography. One such example is the TMS derivatization of sugars and oligosaccharides, compounds with many hydroxyl groups, followed by GC analysis.
Detectors detect components separated by gas chromatograph columns and are used for different purposes.
Flame Ionization Detector (FID) detects ionized compounds by combustion of organic compounds in a hydrogen flame formed by air and hydrogen. Almost all organic compounds can be detected, and the sensitivity is extremely high.
Thermal Conductivity Detector (TCD) defects components by reading the temperature change of a filament based on the difference in thermal conductivity between the carrier gas and the target component. Both inorganic and organic components can be detected nondestructively.
Thermal Conductivity Detector (TCD) detects each component by amplifying the light of a specific wavelength generated from the element by combustion using a photomultiplier tube and converting the intensity of the light into an electrical signal. Sulfur compounds, phosphorous compounds, and organotin compounds can be detected.
Sulfur components are detected by measuring the light produced when chemical species (mainly SO) converted from sulfur compounds are excited by ozone and then return to their ground state using a photomultiplier tube.
This detector is suitable for the measurement of organic nitrogen compounds. When a compound containing phosphorus or nitrogen enters the rubidium salt in the hydrogen flame, it ionizes to form CN- and PO- ions, which are detected.
This detector is used for the selective detection of compounds with high neoelectronicity, such as organohalogen compounds, organometallic compounds, and nitro compounds. Components are detected by reading changes in voltage values to keep the ion current collected in the collector constant.
A gas chromatograph-mass spectrometer is an instrument that combines a gas chromatograph and a mass spectrometer via an interface. First, a sample containing multiple components is separated into single components by the gas chromatograph, and then the mass spectrometer measures the MS spectra of the individual components to qualify the components and quantitate them from the spectral intensity of the ions.
Gas chromatograph-mass spectrometers are suitable for compositional analysis of various oils, qualitative analysis of organic solvents, qualitative and quantitative analysis of gases generated from various materials and pyrolysis-generated gas species, and VOC (volatile organic compounds) analysis in air, water, etc.
*Including some distributors, etc.
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PerkinElmer Inc., founded in 1937, is an American manufacturer headquartered in Waltham, Massachusetts, specializing in laboratory technology and management. The company's product offerings include analysis and characterization instruments, software, and consumables. Such offerings cover chromatography, mass spectrometry, molecular and atomic spectroscopy. They also provide immunoassay and food quality analyzers, as well as the simultaneous thermal analyzer (STA). These products find applications in various industries, such as biopharmaceuticals, food safety, lithium battery, and water resource management. PerkinElmer also offers OneSource Laboratory Services, providing knowledge, application, and service solutions for scientific laboratories. Additionally, their LABStartUp program supports new laboratories with instrumentation, consumables, and funding.
ELGA LabWater, the brand name of Veolia Water Solutions & Technologies and a subsidiary of Veolia Water UK Limited, is a British manufacturer, founded in 1937 and headquartered in Lane End, High Wycombe, specializing in water purification solutions. The company develops clinical and laboratory water purification systems under the MEDICA and PURELAB brands. Additionally, the company offers modular water purification and distribution systems under the CENTRA brand. It also caters to specific applications with water purification systems, including BIOPURE for healthcare applications and PURENERGY 30 for mission-critical purposes. These purification solutions find laboratory applications, for example in atomic absorption spectrophotometry (AAS) research.
PAC L.P. was founded in 1931 in Houston, Texas, USA, as a manufacturer of advanced analytical instruments for gas chromatography, elemental analysis, physical properties, and fuel composition. The product list of the company consists of ElemeNtS, JFTOT IV, OptiDist, OptiFlash, and Reformulyzer M4. The products represent a cutting-edge solution for conducting atmospheric distillation and efficiently detecting total sulfur and total nitrogen across various states of matter, including solids, liquids, gases, and LPG samples, thereby enhancing both fuel analysis precision and laboratory efficiency. The company serves various industries, including chemicals, petroleum, analytical laboratories, environmental monitoring, and quality control.
GERSTEL, Inc., founded in 1967, is an American manufacturer based in Linthicum Heights, Maryland, specializing in developing and producing systems and solutions for chemical analysis. The company’s product range encompasses cooled injection systems (CISs), gas chromatographic (GC) preparative fraction collectors, multidimensional gas chromatography solutions, olfactory detection ports, and pyrolysis systems. It also develops software for sample preparation, method development and analytical efficiency. The company caters to various industries, including biotechnology and pharmaceuticals, chemicals and polymers, environmental analysis, food and beverages, as well as forensics and clinical research. Some of its notable clientele are LECO Corporation, Supelco, Inc., Syft Technologies, and Tufts University.
Agilent Technologies, Inc. is a global supplier headquartered in Santa Clara, California, that provides instruments, software, services, and consumables for laboratories, was established in 1999 as a spin-off from Hewlett-Packard. The company serves analytical laboratories and the clinical and routine diagnostics markets with a full suite of technology platforms. These include automation, bioreagents, gas and liquid chromatography, informatics, and vacuum technologies. They provide critical tools and capabilites that help customers address some of humanity’s biggest challenges including disease detection and therapeutics, environmental health, and food safety.
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
New Cosmos Electric, a company founded in 1934 and headquartered in Osaka, Japan, is a manufacturer and supplier of gas detectors and alarm systems. The company's product portfolio includes portable gas detectors, odor sensors, steel dust meters, air quality monitors, and gas detection and alarm systems. These products are utilized by various industries, including the energy industry, steel, construction, transportation, and livestock industries. The company is both ISO 14001 and ISO 9001 certified, with offices and distributors in the USA, Thailand, France, Europe, and Brazil.
Drawell Instrument Co., Ltd. was founded in 1999 in Yuzhong District, Chongqing, China, as a manufacturer and seller of laboratory equipment and scientific instruments. The product list of the company consists of a digital viscometer, laboratory refrigerator, flame photometer, and anaerobic workstation, among others. The equipment serves diverse industries, ensuring liquid viscosity for quality, controlling temperature-sensitive materials, measuring element concentrations, and supporting anaerobic bacteria research. The company caters to various industries, including petroleum, chemical, electric power, textile, metallurgy, and textile.
Founded in 1890 in Missouri, Emerson Electric Co., is a technology and engineering company that provides various solutions for customers in industrial, commercial, and consumer markets globally. Business segments include automation solutions, AspenTech, and commercial & residential solutions segments. The Automation Solutions segment offers measurement and analytical instrumentation, industrial valves and equipment, and process control software and systems. The AspenTech segment provides asset optimization software for enhancing performance through a combination of modeling, simulation, and optimization capabilities. The Commercial & Residential Solutions segment offers residential and commercial HVAC products, system protector and flow control devices, and IoT thermostats.
Ranking as of June 2025
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | PAC L.P. |
19.9%
|
| 2 | Drawell Instrument Co., Ltd |
11.2%
|
| 3 | Emerson Electric Co. |
10.7%
|
| 4 | ELGA LabWater. |
10.2%
|
| 5 | PerkinElmer Inc. |
9.9%
|
| 6 | GERSTEL, Inc. |
9.1%
|
| 7 | Nissha FIS, Inc |
6.1%
|
| 8 | New Cosmos Electric |
5.9%
|
| 9 | Agilent Technologies |
5.4%
|
| 10 | Thermo Fisher Scientific Inc. |
5.3%
|
Derivation Method
The ranking is calculated based on the click share within the chromatographic gas page as of June 2025. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
Newly Established Company
Company with a History
*Including some distributors, etc.
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
|
United States of America
|
6 | 60.0% |
|
Japan
|
3 | 30.0% |
|
China
|
1 | 10.0% |
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